Yini i-TAGMe
Emhlabeni jikelele okukhethekile: I-Tumor Aligned General Methylated Epiprobe (TAGMe)
Ekuqinisekisweni kwamasampula omtholampilo angaphezu kuka-3000, izinga le-methylation le-TAGMe ezicutshini zesimila laliphezulu kakhulu kunalelo lezicubu ezivamile.Ngakho-ke, i-TAGMe ingasetshenziswa njengomaka womdlavuza we-pan-cancer ukuze kutholwe izinhlobo zomdlavuza.
Izakhi zofuzo ezihlobene ne-histone zine-hypermethylated kumdlavuza wamaphaphu futhi i-hypermethylated HIST1H4F ingasebenza njenge-pan-cancer biomarker.
————Ucwaningo Lomdlavuza,IF:12.7
Deukusebenza kwe-tection
Njengomaka womdlavuza we-pan-cancer, i-TAGMe inokucaciswa okuphezulu nokuzwela ekuqinisekiseni isampula yomtholampilo, enereferensi yenani elibalulekile ekuxilongweni komtholampilo kwamathumba.
I-TAGMe iyazwela kumasampuli ahlukene wesimila uma ukucaciswa kungaphezu kuka-95%,