Muva nje, i-Shanghai Epiprobe Biotechnology Co., Ltd. (ebizwa ngokuthi “Epiprobe”) imemezele ukuthi isiqede cishe izigidi eziyi-RMB 100 ku-Series B financing, etshalwe ngokuhlanganyela yinhloko-dolobha yezimboni, izinkundla zokutshala izimali zikahulumeni kanye nenkampani esohlwini ye-Yiyi Shares (SZ). :001206).
Yasungulwa ngo-2018, i-Epiprobe, njengomsekeli kanye nephayona lokuhlolwa komdlavuza we-pan-cancer kusenesikhathi, iyibhizinisi lobuchwepheshe obuphezulu eligxile ekuxilongweni kwamangqamuzana omdlavuza kanye nemboni yezokwelapha enembile.Yakha eqenjini eliphezulu lochwepheshe be-epigenetics kanye nokuqongelela okujulile kwezemfundo, i-Epiprobe ihlola umkhakha wokutholwa komdlavuza, isekela umbono "wokugcina wonke umuntu ekude nomdlavuza," ukuzibophezela ekutholakaleni kusenesikhathi, ukuxilongwa kusenesikhathi kanye nokwelashwa komdlavuza kusenesikhathi, ngaleyo ndlela kuthuthukiswe ukusinda. izinga leziguli ezinomdlavuza ukuthuthukisa impilo yabantu bonke.
Ngemva kokumba iminyaka engu-20, ithimba eliyinhloko le-Epiprobe lazitholela ngokuzimela uchungechunge lomdlavuza oluhambisana ne-Aligned General Methylated Epiprobes (TAGMe), elitholakala yonke indawo kumdlavuza ohlukahlukene, ngaleyo ndlela lwandisa kakhulu inkambu yohlelo lokusebenza.
Mayelana nobuchwepheshe bokubona, i-pyrosequencing ngokwesiko ithathwa “njengendinganiso yegolide” yokutholwa kwe-methylation, yona nokho ethembele ekuguquleni i-bisulfite, kodwa ifaka phakathi ukushiyeka okunjengokusebenza kahle kokuguqulwa okungazinzile, ukucekelwa phansi kwe-DNA okulula, izidingo eziphezulu zama-opharetha, nokuncika kumathuluzi abalulekile.Lokhu kushoda kukhawulela ukusetshenziswa kwayo.I-Epiprobe, ngokwenza ukuphumelela kwezobuchwepheshe, ngokuzimela ithuthukise ubuchwepheshe obusha bokuthola i-methylation - i-Me-qPCR ngaphandle kokwelashwa kwe-bisulfite, okwehlisa izindleko futhi kuthuthukise ukutholakala kokuqina nokusebenza komtholampilo, okwenza ukutholwa kube lula futhi kube lula.
I-Epiprobe, egxile kumaka omdlavuza we-pan-cancer ayinhloko nezindlela zokuthola i-methylation, isebenzise amalungelo obunikazi angaphezu kuka-50 asekhaya nawamazwe ngamazwe, futhi ithole ukugunyazwa kokusungula umenzi oqinile welungelo lobunikazi.
Njengamanje, i-Epiprobe isebenze eduze nezibhedlela eziphezulu ze-40 e-China, okuhlanganisa i-Zhongshan Hospital, i-International Peace Maternity kanye neSibhedlela Sezempilo Yezingane, kanye neSibhedlela sase-Changhai njll, futhi isebenzise ukuhlelwa kwemikhiqizo ebanzi kumdlavuza wepheshana lokuzala (okuhlanganisa nomdlavuza womlomo wesibeletho, umdlavuza we-endometrial) , umdlavuza we-urothelial (okuhlanganisa umdlavuza wesinye, umdlavuza we-urethra, umdlavuza we-renal pelvis), umdlavuza wamaphaphu, umdlavuza wegilo, umdlavuza we-hematological kanye neminye imidlavuza.Ukuqinisekiswa okuyizimpumputhe okuphindwe kabili sekusetshenziswe kumasampula omtholampilo angama-70,000 anezinhlobo ezingama-25 zomdlavuza.
Phakathi kwemikhiqizo, emikhiqizweni yokutholwa komdlavuza wepheshana lokuzala labesifazane, ukuqinisekiswa okuyimpumputhe okuphindwe kabili kuye kwasetshenziswa kumasampula omtholampilo angaphezu kuka-40,000, futhi uchungechunge lwemiphumela yocwaningo lushicilelwe kumajenali ezemfundo adumile emhlabeni jikelele afana neCancer Research, Clinical and Translational Medicine, kanye uvivinyo lwemitholampilo lwezinga elikhulu lwezikhungo eziningi luyenziwa.Njengoba i-R&D ithuthuka futhi nezinsiza zikhula njalo, ipayipi lomkhiqizo wenkampani likhula kancane kancane.
UNksz. Hua Lin, oyi-CEO ye-Epiprobe waphawula ukuthi: “Kuwudumo lwethu olukhulu ukuqashelwa nokusekelwa izikhulu zezimboni ezinhle kakhulu.I-Epiprobe ibonakala ngokuqongelela kwayo okujulile kwezemfundo, ubuchwepheshe obuyingqayizivele, kanye nocwaningo oluqinile lwezokwelapha, oluzuze ukwethenjwa amaqembu amaningi.Eminyakeni emine edlule, ithimba lenkampani kanye nokusebenza kuye kwaba ngcono kakhulu.Ezinsukwini ezizayo, ngeke senze umzamo wokumema ozakwethu abaningi abanomqondo ofanayo ukuze basebenzisane futhi basebenze ndawonye, ngaleyo ndlela sikhuthaze njalo i-R&D kanye nenqubo yesicelo sokubhalisa, kanye nokuhlinzeka odokotela neziguli ngezinsizakalo ezingcono kakhulu zokuhlola umdlavuza kanye imikhiqizo.”
Isikhathi sokuthumela: Apr-11-2022